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Dr Benjamin Chuah is a medical oncologist at Gleneagles Hospital, Singapore.
His subspecialties are in gastrointestinal cancers, including oesophageal, gastric, biliary tract, pancreatic, liver (hepatocellular carcinoma), neuroendocrine cancers and colorectal cancers.
Dr Chuah graduated from Trinity College Dublin, Ireland. He returned to Singapore and obtained his membership in the Royal College of Physicians, UK. He has more than 25 years of clinical practice.
Before entering private practice, he was involved in both post-graduate teaching and research. He was the director of post-graduate medical education (medical oncology) and a core faculty for the residency programme (internal medicine) at the National University Hospital (NUH).
Dr Chuah was also involved in clinical and translational research for many years and was the principal or co-investigator in international trials involving the use of novel and targeted therapy drugs for colorectal and pancreatic cancer.
As a clinical cancer specialist and researcher, his research work includes small cell gallbladder cancer with paraneoplastic hyponatremia, exploring the lack of somatic mutations in VEGFR-2 tyrosine kinase domain in hepatocellular carcinoma, renal cell carcinoma (kidney cancer) with bony metastases, and the use of the chemotherapy drug, docetaxel with or without ketoconazole in breast cancer.
Dr Chuah has published on screening in colorectal cancer and was involved in a randomised, phase 2 study of ganitumab or conatumumab in combination with FOLFIRI (5-FU, leucovorin, irinotecan) for second-line treatment of mutant KRAS metastatic colorectal cancer.
He was awarded the NUH Innovative Grant for research in warfarin pharmacogenomics and was also honoured with the inaugural Kobayashi Foundation Award for his work on serial changes in the expression of breast cancer-related proteins in response to neoadjuvant chemotherapy. His research work has led to several first-author publications in medical and oncology journals, including Gastroenterology, GUT, and Annals of Oncology.